What is Repatha®?1
Repatha® is a medicine that lowers levels of ‘bad’ cholesterol (LDL-C) in the blood.
How does it work?
Your liver helps to take LDL-C out of your blood. The liver then breaks down the LDL-C.2
The liver also makes a protein called PCSK9. PCSK9 regulates the amount of LDL-C your liver mops up. When the liver doesn't take the LDL-C in to break it down, the LDL-C stays in the blood and can build up in your arteries. Over time, this build-up can cause serious health problems.2
Repatha® contains the active substance evolocumab, a monoclonal antibody (a type of specialised protein designed to attach to a target substance in the body). Evolocumab is designed to attach to the PCSK9 protein, bringing down its levels. This means that more cholesterol enters the liver and so helps lower the level of cholesterol in the blood.2