What is Repatha® (evolocumab) and what is it used for?

Repatha® is a medicine that lowers levels of ‘bad’ cholesterol (LDL-C), a type of fat, in the blood.
Repatha® contains the active substance evolocumab, a monoclonal antibody (a type of specialised protein designed to attach to a target substance in the body).
Evolocumab is designed to attach to a substance called PCSK9 that affects the liver’s ability to take in cholesterol. By the medicine attaching to, and mopping up, PCSK9, more cholesterol enters the liver and so lowers the level of cholesterol in the blood.
Repatha® is used in patients who cannot currently control their cholesterol levels with diet and medication.
You should stay on your cholesterol-lowering diet while taking this medicine. Repatha® may be used with other medicines that lower your levels of cholesterol.

This site is intended for patients in Ireland who are being treated with an Amgen® product and for Irish Healthcare Professionals (HCPs).

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IE-CBU-0820-00002 August 2020