How should Repatha® (evolocumab) be stored and what's in the carton?

More extensive information on Repatha® administration is available in the Patient Information Leaflet (PIL)
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the label and carton after EXP. The expiry date refers to the last day of that month.
Store in a refrigerator (2°C to 8°C). DO NOT freeze.
Store in the original carton in order to protect from light.
Your pre-filled pen may be left outside the refrigerator to reach room temperature (up to 25°C) before injection. This will make the injection more comfortable. After removal from the refrigerator, Repatha® may be stored at room temperature (up to 25°C) in the original carton and must be used within 1 month.
Do not use the pre-filled pen if it has been dropped on a hard surface. Part of the pre-filled pen may be broken even if you cannot see the break.
Do not try to warm the pre-filled pen by using a heat source such as hot water or microwave.
Do not throw away any medicines via wastewater or household waste.
Ask your doctor, pharmacist or nurse how to dispose of medicines you no longer use. These measures will help protect the environment.

Contents of the pack and other information
The active substance in Repatha® is evolocumab. Each SureClick® pre-filled pen contains 140 mg of evolocumab in 1 ml of solution. The other ingredients are proline, glacial acetic acid, polysorbate 80, sodium hydroxide, water for injections.
Repatha® is a solution which is clear to opalescent, colourless to yellowish, and practically free from particles. Do not use this medicine if you notice it is discoloured or contains large lumps, flakes or coloured particles.
Each pack contains two single-use SureClick® pre-filled pens.

This site is intended for patients in Ireland who are being treated with an Amgen® product and for Irish Healthcare Professionals (HCPs).

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IE-CBU-0820-00002 August 2020