Considerations before starting Neupogen

Your doctor will take you through the things you need to consider when preparing to take Neupogen®. Further information is also available in the Neupogen® Patient Information Leaflet.

Things to consider when starting on Neupogen®1

Do not use Neupogen®:

  • if you are allergic to filgrastim or any of the other ingredients of this medicine (sodium acetate, sorbitol (E420), polysorbate 80, water for injections).

Please tell your doctor before starting treatment if you have:

Sickle cell anaemia, as Neupogen® may cause sickle cell crisis.
An allergy to natural rubber (latex). The needle cover on the syringe may be made from a type of natural rubber and may cause allergic reactions.
Osteoporosis (bone disease).
If you are a patient with severe chronic neutropenia, you may be at risk of developing cancer of the blood (leukaemia, myelodysplastic syndrome (MDS)). You should talk to your doctor about your risks of developing cancers of the blood and what testing should be done. If you develop or are likely to develop cancers of the blood, you should not use Neupogen®, unless instructed by your doctor.

Other medicines and Neupogen®

  • Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
  • Take special care with other products that stimulate white blood cells: Neupogen® is one of a group of products that stimulate the production of white blood cells. Your healthcare professional should always record the exact product you are using.

Pregnancy and breast-feeding

Neupogen® has not been tested in pregnant or breast-feeding women. Neupogen® is not recommended during pregnancy.
It is important to tell your doctor if you:
  • Are pregnant or breast-feeding;
  • Think you may be pregnant; or
  • Are planning to have a baby.
If you become pregnant during Neupogen® treatment, please inform your doctor.
Unless your doctor directs you otherwise, you must stop breast feeding if you use Neupogen®.

Driving and using machines

Neupogen® may have a minor influence on your ability to drive and use machines. This medicine may cause dizziness. It is advisable to wait and see how you feel after taking Neupogen® and before driving or operating machinery.


  1. Neupogen® (filgrastim). Patient Information Leaflet. [Available at:]